Project Description

This project addresses the need for phosphoproteomic tools in personalized medicine using kinase inhibitors. We will target an oncogenic pathway having eight abberantly phosphorylated sites informative of a patient´s susceptibility to treatment. MIPs recognizing these sites will be developed in the form of porous beads or nanoparticles and characterised with respect binding affinity at both peptide and protein level and compared with traditional antibody based detection. Ultimately a MIP-MS multiplex assay will be developed and assessed on clinical samples jointly with other partners.

Candidate requirements

The successful candidate will have a masters’ degree (or equivalent) in polymer/organic chemistry, bioanalytical protein/peptide science or another related field.  Experimental laboratory experience is required and candidates with interdisciplinary experience directly related to the research topic of the position outlined above, notably synthetic receptors and molecular imprinting technology will be given preference. 

Supervisor information

Börje Sellergren, Professor in Biomedical Technology, Biofilms Research Center for Biointerfaces, Department of Biomedical Sciences, Malmö University.

Phone: +46 40 665 7810

Mail: borje.sellergren@mau.se

URL: https://mau.se/en/research/research-centres/biofilms-research-centre-for-biointerfaces/