DC 9

Designer-protein binders for pan-specific or sequence specific enrichment of pHis, meHis and meLys PTMs

Project Description

The Protein Research Group at the University of Southern Denmark (SDU) in Odense is seeking a skilled DC to join our team. This role is pivotal in supporting the development of novel affinity-binders for high-sensitivity proteomics and biomedical applications in cancer.  DC9 will use protein design concepts and deep-learning computational methods to develop novel protein-based affinity-binders for detection and quantification of post-translational modifications in proteins and peptides.

Produce, purify and test selected designer proteins for enrichment of cancer biomarkers and to understand cellular signalling pathways involving post-translational modifications, including methylated and phosphorylated protein species.

Supervisor information

Professor Ole Nørregaard Jensen
Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark

Host Institution

Secondments

  • Malmö University Sweden 2 months
  • ReSyn Biosciences South Africa 1 month
  • University of Pavia Italy 1 month
  • Proteome Sciences Germany 1 month

Degree awarding Institution

  • University of Southern Denmark

DC9 Huilin Li