Project Description

This doctoral project focuses on the design and synthesis of ultrabright, magnetic molecularly imprinted polymer nanoparticles (nanoMIPs) targeting glycosylated tumour antigens such as sialic acid, STn, and Tn. You will develop nanoMIPs for rare cell isolation using flow cytometry (FACS) and magnetic capture, enabling single-cell and multiomics analysis of circulating tumour cells (CTCs). The work combines advanced polymer synthesis, nanoparticle engineering, and material characterisation, with applications in liquid biopsies. Close collaboration with interdisciplinary partner teams will support integration into proteomics workflows and biomarker discovery, contributing to the advancement of precision oncology.

Supervisor information

Knut Rurack, Head of Chemical and Optical Sensing Division, Department of Analytical Chemistry; Reference Materials, Bundesanstalt für Materialforschung und prüfung (BAM), Berlin, Germany.

Phone: +49 30 8104 1190 

Mail: knut.rurack@bam.de

URL: https://www.bam.de/Navigation/EN/About-us/Organisation/President/Department-1/Division-19/division19.html